Maternal and offspring adiposity-related genetic variants and gestational weight gain
نویسندگان
چکیده
منابع مشابه
Maternal obesity, gestational weight gain, and offspring adiposity: the exploring perinatal outcomes among children study.
OBJECTIVE To determine whether adequate vs excessive gestational weight gain (GWG) attenuated the association between maternal obesity and offspring outcomes. STUDY DESIGN Data from 313 mother-child pairs participating in the Exploring Perinatal Outcomes among Children study were used to test this hypothesis. Maternal prepregnancy body mass index (BMI) and weight measures throughout pregnancy...
متن کاملMaternal Obesity, Gestational Weight Gain, and Asthma in Offspring
INTRODUCTION Obesity is common among women of childbearing age; intrauterine exposure to maternal obesity or gestational weight gain may influence the development of asthma in early childhood. We examined the relationships of maternal obesity and gestational weight gain with asthma in offspring. METHODS We used data from the Early Childhood Longitudinal Study-Birth Cohort, which has a nationa...
متن کاملMaternal Gestational and Postdelivery Weight Gain and Child Weight.
BACKGROUND Maternal gestational weight gain (GWG) is a risk factor for the development of overweight in her child. It is unknown whether GWG programs the child's health or whether GWG indicates a shared familial lifestyle during childhood. To disentangle these influences, we studied the association of GWG and postdelivery maternal weight change simultaneously with child's weight development. ...
متن کاملMaternal pre-pregnancy BMI and gestational weight gain, offspring DNA methylation and later offspring adiposity: findings from the Avon Longitudinal Study of Parents and Children
BACKGROUND Evidence suggests that in utero exposure to undernutrition and overnutrition might affect adiposity in later life. Epigenetic modification is suggested as a plausible mediating mechanism. METHODS We used multivariable linear regression and a negative control design to examine offspring epigenome-wide DNA methylation in relation to maternal and offspring adiposity in 1018 participan...
متن کاملGestational weight gain and child adiposity at age 3 years.
OBJECTIVE The purpose of this study was to examine the associations of gestational weight gain with child adiposity. STUDY DESIGN Using multivariable regression, we studied associations of total gestational weight gain and weight gain according to 1990 Institute of Medicine guidelines with child outcomes among 1044 mother-child pairs in Project Viva. RESULTS Greater weight gain was associat...
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ژورنال
عنوان ژورنال: The American Journal of Clinical Nutrition
سال: 2011
ISSN: 0002-9165,1938-3207
DOI: 10.3945/ajcn.110.010751